Pramipexole: ADHD

This drug is a d3 preferring dopamine agonist, over time desensitisation of autoreceptors occurs, dopamine uptake is inhibited boosting transmission.
This drug is a powerful motivator, gives optimism to complete goals and banishes boredom in favour of stereotypy and a CRAZY FAST INNER MONOLOGUE - my experience.
Anybody else think dopamine agonists should be a first line for ADHD??

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  1. 1 month ago
    Anonymous

    ok

  2. 1 month ago
    Anonymous

    >Pramipexole (and related D3-preferring dopamine agonist medications such as ropinirole) can induce "impulsive-compulsive spectrum disorders"[8] such as compulsive gambling, punding, hypersexuality, and overeating, even in people without any prior history of these behaviours.

  3. 1 month ago
    Anonymous

    KEK go on and take D3 agonists if you want to become a schizo pyromaniac wandering around like a homeless moron

  4. 1 month ago
    Anonymous

    Just take vitamin d3, 10,000iu of it with a fatty meal in the morning, such as milk.

    "This study continues to establish vitamin D as an important differentiation agent for developing dopamine neurons, and now for the first time shows chronic exposure to the active vitamin D hormone increases the capacity of developing neurons to release dopamine."

    I have adhd, too many side effects from the pills. So instead I take vitamin d3, only 10k of it, I'm now able to stay awake throughout the entire day with it.

    Take 10mg of melatonin prior to sleep. Angle your bed, I put coasters under mine so I don't get acid reflux anymore.

    The vitamin d3 takes around a year before it fully builds up in the body.

    • 1 month ago
      Anonymous

      shut the frick up you massive moron. Only literaly cancer patients take that high dosages of melatonin

      • 1 month ago
        Anonymous

        10mg is safe, otherwise why is it sold on Amazon as a common dosage.

        • 1 month ago
          Anonymous

          it is not at all a common dosage. A high physiological dosage of melatonin would be 500mcg, and even that doesn't promote sleep, it only advances the circadian clock if you take it daily.
          >Amazon
          You should get something like circadin prescribed instead if you have genuine insomnia. Imagine ordering this shit off amazon. They don't even have to send in lab tests you fricking dumbass. Probably contaminated with all kinds of byproducts

          • 1 month ago
            Anonymous

            From personal experience
            >1mg
            Still awake, can't sleep
            >2mg
            Still awake, can't sleep
            >3mg
            Still awake, can't sleep
            >4mg
            Still awake, can't sleep
            >5mg
            I fall asleep within an hour
            >10mg
            I fall asleep within an hour, but I feel better compared to 5mg.

            Also, you're a pretty stupid person, even doctors recommend taking 3mg of melatonin, last time I checked. I bet you were one of the morons that got vaccinated and made fun of people for not taking it.

            I bet you got didn't even know that N acetly cysteine prevents the spike protein from the vaccine from attaching itself to the ace2 receptors on your organs, therefore preventing the vaccine itself to cause any organ damage.

            I know what I'm talking about from personal experience.

          • 1 month ago
            Anonymous

            Same vibes as "aspartame" and "processed" sugar posters

            Also, to prove to you that vitamin d3 works, I've been able to stop myself from eating food, which means I have more dopamine in my brain compared to before so I can muster the willpower to not eat food.

            It should take 2 or 3 months on it, with a fatty meal to better absorb, before you start to notice effects. I would only go as high as 10k in pill form a day, you can just sit outside an get some sunlight so your body can produce more on it's own.

            I'm just happy that I don't get as mad as often, I'm more patient with myself, and I can get more work done. I believe the melatonin helps significantly in giving me a proper sleep that allows me to feel well rested. But the vitamin d3 is what does 80% of the work in making me feel better, less mad, more patient, more energetic.

            I can actually stay awake now for the entire day, I couldn't do that before at all. Give it 2 or 3 months on it before you quit, you'll notice you become a more patient, energetic, calmer person. I'm actually able to read an entire chapter of my general chemistry book and several chapters of the Bible easier, without become as impatient as I once did and slamming both books shut.

            Next thing you're gonna say is that you only need 1mg of adderal because anything higher is too dangerous, bullshit, whatever.

            There's little to no research data on the long-term effects of high-dosage usage of melatonin; all we have is short-term and in patients with cancer. Reasonable doctors usually describe circadin given that its pharmacokinetics are well studied in patients with narcolepsy.
            >I bet you got didn't even know that N acetly cysteine prevents the spike protein from the vaccine from attaching itself to the ace2 receptors on your organs, therefore preventing the vaccine itself to cause any organ damage.
            I'm so glad you've managed to memorise this simple pathway. In fact, you're so proud of your little concoction and discovery that you've repeated it almost verbatim 3 times this week https://warosu.org/sci/?task=search&ghost=false&search_text=N+acetly+cysteine+ace2
            For the record, it's N-[math]textbf{acetyl}[/math]-cysteine ;). Keep learning, my dyslexic friend!
            >I fall asleep within an hour, but I feel better compared to 5mg.
            Have you ever considered that these pills might not actually contain 10mg of melatonin? After all, they don't have to provide lab reports.
            The hepatotoxic side effects from contamination are not some schizophasia either, unlike your post. Adverse effects from supplements have led to an average of about 23,000 ER visits per year (https://www.nejm.org/doi/full/10.1056/NEJMsa1504267).
            >even doctors recommend taking 3mg of melatonin
            Generally untrue, not to mention that you don't care what doctors recommend anyway. After all, you supplement well over twice the safe upper limit of vitamin D3.
            >All that strawmanning
            To be expected from a child with ADHD who refuses to take his medication. And going off on an off-topic tangent about the vaccine is just the icing on the cake. You'll end up just like pic rel.

            Have some humility and maybe you could learn something new. I have faith in you, anon.

          • 1 month ago
            Anonymous

            bullshitter, instead of giving op advice you just critique

          • 1 month ago
            Anonymous

            The post clearly isn't directed towards OP nor is OP asking for advice. Come on, anon, you're smarter than that 😉

          • 1 month ago
            Anonymous

            Next thing you're gonna say is that you only need 1mg of adderal because anything higher is too dangerous, bullshit, whatever.

          • 1 month ago
            Anonymous

            Same vibes as "aspartame" and "processed" sugar posters

    • 1 month ago
      Anonymous

      Also, to prove to you that vitamin d3 works, I've been able to stop myself from eating food, which means I have more dopamine in my brain compared to before so I can muster the willpower to not eat food.

      It should take 2 or 3 months on it, with a fatty meal to better absorb, before you start to notice effects. I would only go as high as 10k in pill form a day, you can just sit outside an get some sunlight so your body can produce more on it's own.

      I'm just happy that I don't get as mad as often, I'm more patient with myself, and I can get more work done. I believe the melatonin helps significantly in giving me a proper sleep that allows me to feel well rested. But the vitamin d3 is what does 80% of the work in making me feel better, less mad, more patient, more energetic.

      I can actually stay awake now for the entire day, I couldn't do that before at all. Give it 2 or 3 months on it before you quit, you'll notice you become a more patient, energetic, calmer person. I'm actually able to read an entire chapter of my general chemistry book and several chapters of the Bible easier, without become as impatient as I once did and slamming both books shut.

    • 1 month ago
      Anonymous

      >Just

  5. 1 month ago
    Anonymous

    No, you want an antagonist, blocking, to force morphic permanent changes in the brain, albeit you will get dementia from it.

    You want the drug that does the opposite of what you want. Once removed from the system, you will get its benefits permanently. But be warned, nightmares yet to have taken form will become you

    • 1 month ago
      Anonymous

      so what, intuniv or quetiapine

  6. 1 month ago
    Anonymous

    Ritalin is better.

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